Vaccines (God’s Plan)

Vaccines (God’s Plan)


They infectin’ infectin’ infectin’ infectin’ infectin’ on me I been vaccinated, it’s no trouble for me Tryna keep it healthy is a struggle to me Don’t worry ’bout cost ’cause it’s all free Kill a pathogen and then inject it in me I don’t want the flu to infect me Breaking in my cell and making copies in me Hope I got people that understand me Do it or you’ll mess up herd immunity Herd Immunity is what makes vaccines a powerhouse against infectious disease in the modern era The basic concept behind herd immunity is that is provides protection for those who can’t receive the vaccine due to any number of contraindications such as egg allergies or pregnancy It also protects the small percentage of people who fail to develop immunity after receiving the vaccination for whatever reason It also protects those who choose not to get the vaccination even when it is readily accessible But you should still get vaccinated since diseases can make a comeback after a lull in immunizations Vaccines, vaccines It gon’ hurt sometimes it won’t I might cry sometimes I don’t I get sick sometimes I know Get a shot for HPV And another for HepB Now make one for HIV And still Vaccines There’s a lot of bad things That infectin’ infectin’ infectin’ infectin’ infectin’ on me Vaccines There’s a lot of adjuvants That enhancin’ enhancin’ enhancin’ enhancin’ enhancin’ in me An adjuvant is a substance that improves the effects of a vaccine by enhancing the immune response caused by the vaccine Adjuvants could be anything from salts to lipids The adjuvant by itself is relatively ineffective, but when combined with the vaccine, it greatly improves response As we can see from these graphs the vaccine by itself provides modest response the adjuvant provides no response But when you add the vaccine and the adjuvant together the response skyrockets Adjuvants are mostly used in subunit vaccines and typically fall in two categories Vehicles, which deliver antigens to the target sites of the immune system or, immunostimulants, which directly affect the immune system Aight, now let’s run that back! She say do you love me, I tell her only partly I only love my shots and my Band-Aid I’m sorry Antibody, even got it tatted on me Louis Pasteur, my man really is the OG And you know me Get some IgA with the IgG Thank God that we almost polio free Without Sulk and Enders there’d be no me Before the development of vaccines for polio there were upwards of 20,000 cases of paralytic polio annually in the US and 500,000 worldwide In the 20th century, two vaccines were developed against polio IPV prevented the disease from occurring while OPV prevented the virus from actually infecting a person Since then, polio has been eliminated from the US and only three countries in the whole world are endemic for it That means there’s no wild polio floating around here in America Like at all We can get rid of whole ass infectious diseases thanks to vaccine Vaccines, vaccines It gon’ hurt sometimes it won’t I might cry sometimes I don’t It don’t take no time at all Killing worms is quite easy But without immunity They gon’ be back instantly The ultimate shademaster known as the Cochrane Review roasts the deworming movement stating that “…the belief that deworming will impact substantially on economic development seems delusional when you look at the results of reliable controlled trials” While trials have shown that worms can indeed be eliminated in an individual, the lack of natural immunity results in rapid reinfection This fact in it of itself poses a challenge to vaccine development as many of our current vaccines piggyback on natural pathways to immunity Furthermore, the high rate of antigenic shift coupled with intense unhelpful stimulation of the immune system and sheer size of the worm makes it even harder to mount a successful attack let alone induce immunity But don’t give up hope just yet Some successes have been observed in attempts to attack the larval stages of worm infections And still Vaccines There’s a lot of bad things That infectin’ infectin’ infectin’ infectin’ infectin’ on me Vaccines There’s a lot of adjuvants That enhancin’ enhancin’ enhancin’ enhancin’ enhancin’ in me

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About the Author: Emmet Marks

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